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Edward K Geissler Selected Research

gluconic acid (gluconate)

1/2021Cancer-associated cells release citrate to support tumour metastatic progression.
1/2019Potential Use of Gluconate in Cancer Therapy.
1/2018Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo.

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Edward K Geissler Research Topics

Disease

67Neoplasms (Cancer)
01/2022 - 01/2002
14Neoplasm Metastasis (Metastasis)
01/2020 - 03/2004
13Pancreatic Neoplasms (Pancreatic Cancer)
01/2021 - 03/2004
11Colitis
01/2021 - 01/2006
8Hepatocellular Carcinoma (Hepatoma)
11/2020 - 07/2008
8Colonic Neoplasms (Colon Cancer)
12/2010 - 01/2003
7Melanoma (Melanoma, Malignant)
01/2021 - 09/2002
7Fibrosis (Cirrhosis)
01/2021 - 05/2007
7Inflammation (Inflammations)
01/2021 - 12/2006
6Hypoxia (Hypoxemia)
04/2017 - 03/2007
5Autoimmune Diseases (Autoimmune Disease)
01/2019 - 02/2008
5Stomach Neoplasms (Stomach Cancer)
12/2015 - 03/2007
5Carcinogenesis
11/2013 - 08/2009
4Infections
01/2020 - 10/2002
4Colorectal Neoplasms (Colorectal Cancer)
01/2016 - 03/2004
3Reperfusion Injury
02/2021 - 11/2004
3Ischemia
02/2021 - 11/2004
3Liver Diseases (Liver Disease)
02/2021 - 11/2008
3Wounds and Injuries (Trauma)
11/2020 - 11/2005
3Skin Neoplasms (Skin Cancer)
01/2015 - 11/2010
3Fibrosarcoma
10/2012 - 05/2008
2End Stage Liver Disease
03/2021 - 12/2015
2Hepatitis
01/2021 - 01/2021
2Graft vs Host Disease (Graft-Versus-Host Disease)
12/2019 - 10/2009
2Ulcerative Colitis
06/2015 - 12/2006
2Gastrointestinal Neoplasms (Gastrointestinal Cancer)
02/2012 - 04/2010
2Lymphatic Metastasis
11/2011 - 06/2007
2Tyrosinemias (Tyrosinemia)
05/2010 - 11/2008
2Thrombosis (Thrombus)
06/2005 - 03/2004
1Brain Neoplasms (Brain Tumor)
01/2022

Drug/Important Bio-Agent (IBA)

21Sirolimus (Rapamycin)FDA Link
11/2020 - 02/2002
11TOR Serine-Threonine KinasesIBA
11/2020 - 06/2005
8Transcription Factors (Transcription Factor)IBA
06/2015 - 11/2007
8Immunosuppressive Agents (Immunosuppressants)IBA
11/2013 - 05/2004
8Pharmaceutical PreparationsIBA
06/2011 - 01/2002
7MTOR InhibitorsIBA
11/2020 - 03/2008
7Small Interfering RNA (siRNA)IBA
12/2018 - 05/2007
7Heat-Shock Proteins (Heat-Shock Protein)IBA
07/2012 - 03/2007
6Citric Acid (Citrate)FDA LinkGeneric
01/2022 - 01/2018
6Proteins (Proteins, Gene)FDA Link
01/2021 - 09/2002
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2017 - 02/2002
6Interleukin-13IBA
04/2014 - 05/2007
5Cyclosporine (Ciclosporin)FDA LinkGeneric
11/2013 - 02/2002
5Dextrans (Dextran)FDA Link
12/2011 - 01/2006
4Interleukin-6 (Interleukin 6)IBA
01/2019 - 11/2007
4Messenger RNA (mRNA)IBA
02/2018 - 11/2005
4sodium sulfate (sodium bisulfate)FDA LinkGeneric
05/2011 - 01/2006
4IGF Type 1 Receptor (IGF 1 Receptor)IBA
04/2010 - 11/2007
3gluconic acid (gluconate)FDA LinkGeneric
01/2021 - 01/2018
3CytokinesIBA
12/2020 - 05/2008
3Lactic Acid (Lactate)FDA LinkGeneric
12/2019 - 11/2016
3Mechanistic Target of Rapamycin Complex 2IBA
12/2018 - 04/2010
3RNA (Ribonucleic Acid)IBA
01/2018 - 01/2006
3Phosphotransferases (Kinase)IBA
02/2016 - 07/2008
3Sulfonic AcidsIBA
04/2014 - 05/2007
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
02/2013 - 09/2006
3Epidermal Growth Factor (EGF)IBA
10/2012 - 03/2007
3InterleukinsIBA
12/2011 - 12/2008
3GemcitabineFDA Link
11/2011 - 03/2004
3Insulin-Like Growth Factor I (IGF-1)IBA
12/2008 - 11/2007
317- (dimethylaminoethylamino)- 17- demethoxygeldanamycinIBA
11/2007 - 03/2007
3ErbB Receptors (EGF Receptor)IBA
11/2007 - 03/2007
2Immune Checkpoint InhibitorsIBA
01/2021 - 01/2021
2CollagenIBA
01/2021 - 12/2008
2AntigensIBA
12/2020 - 01/2013
2Calcineurin InhibitorsIBA
11/2020 - 12/2006
2IntegrinsIBA
01/2020 - 11/2005
2Fatty Acids (Saturated Fatty Acids)IBA
01/2020 - 01/2018
2citrate-binding transport proteinIBA
01/2019 - 01/2018
2Conditioned Culture MediaIBA
12/2018 - 01/2014
2Glucose (Dextrose)FDA LinkGeneric
01/2018 - 01/2017
2tyrosine receptor (receptor, tyrosine)IBA
02/2016 - 11/2011
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2016 - 02/2012
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2016 - 11/2007
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
12/2015 - 11/2011
2Interleukin-17 (Interleukin 17)IBA
06/2015 - 12/2011
2LuciferasesIBA
02/2014 - 12/2010
2Interleukin-15 (Interleukin 15)IBA
02/2014 - 01/2014
2Paclitaxel (Taxol)FDA LinkGeneric
01/2014 - 07/2003
2DefensinsIBA
10/2012 - 05/2012
2AzoxymethaneIBA
12/2011 - 05/2011
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
11/2011 - 11/2008
2Tyrosine Kinase InhibitorsIBA
11/2011 - 06/2007
2Activating Transcription Factor 3IBA
12/2010 - 11/2007
2fumarylacetoacetase (fumarylacetoacetate hydrolase)IBA
05/2010 - 11/2008
2NF-kappa B (NF-kB)IBA
04/2010 - 02/2009
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
08/2009 - 11/2008
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
11/2008 - 06/2007
2Focal Adhesion Protein-Tyrosine KinasesIBA
11/2007 - 03/2007
2tanespimycin (17AAG)IBA
11/2007 - 03/2007
2Green Fluorescent ProteinsIBA
03/2004 - 01/2003
1ValganciclovirFDA Link
01/2021

Therapy/Procedure

28Therapeutics
02/2021 - 03/2004
13Transplantation
02/2021 - 11/2008
10Liver Transplantation
03/2021 - 11/2004
10Organ Transplantation
08/2015 - 01/2002
4Heart Transplantation (Grafting, Heart)
01/2020 - 05/2004
2Negative-Pressure Wound Therapy
11/2020 - 11/2019
2Ligation
01/2020 - 03/2017
2Drug Therapy (Chemotherapy)
03/2017 - 03/2004